Slice any large spears in half to make them thinner. Prepare your dredging station by placing the flour, eggs and panko bread crumbs in three different shallow dishes. Season the flour with salt, pepper, garlic powder, and onion powder.
Dredge the pickles first in the flour (shake any excess), then into the eggs (make sure they are fully covered in egg), and lastly into the panko bread crumbs. I like to use two forks to do this so I won't get my fingers dirty.
Let the breaded spears rest for 5-10 mins and pour about ½ inch of oil into a medium-sized skillet. Heat the oil over medium-heat until hot, and fry the spears in batches until golden brown. To test if the oil is hot enough, drop a few bread crumbs into it and if they sizzle, it’s ready. Serve with your favorite dipping sauce.